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Current Enzyme Inhibition

Eiditor-in-Chief

ISSN (Print): 1573-4080
ISSN (Online): 1875-6662

Review Article

Protein Kinases as Drug Targets in Human and Animal Diseases

Author(s): Suvarna G. Kini*, Vikas Garg, Sharada Prasanna, Revathi Rajappan and Muhammad Mubeen

Volume 13 , Issue 2 , 2017

Page: [99 - 106] Pages: 8

DOI: 10.2174/1573408013666161128144216

Price: $58

Abstract

Almost thirty percent of the protein targets currently under exploration and study constitute the protein kinases which have always attracted the pharmaceutical companies as they are easy targets for drug development. Although the kinases will remain major focus of oncology for many years to come in the development of anticancer drugs, the number of kinase inhibitors as therapeutic targets for the treatment of several other diseases which are undergoing clinical trials are exponentially increasing. In this review, we discuss very briefly the different types of protein kinases that have been used as targets for developing drugs for cancer, inflammation, autoimmune disease, heart disease and animal diseases.

Keywords: Cancer, inflammatory and autoimmune diseases, kinases, protein kinases.

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