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Current Pharmaceutical Design

Eiditor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

The Predictive Value of Lipid Markers in Vascular Disease

Author(s): H. J. Milionis, S. S. Daskalopoulou, M. Elisaf and D. P. Mikhailidis

Volume 11 , Issue 17 , 2005

Page: [2209 - 2224] Pages: 16

DOI: 10.2174/1381612054367409

Price: $58

Abstract

Lipid markers are well established predictors of vascular disease. The most frequently measured lipid variables are total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol and triglycerides. In this review we consider the predictive value of these variables and other more specialised related tests. We also discuss the effect of lipid altering drugs on these markers. The interaction of other vascular risk factors and the lipid effects of non-lipid altering drugs (e.g. blood pressure lowering agents) are also briefly described. Similarly, we discuss the effects of lipid lowering drugs on non-lipid vascular risk factors. Finally, we briefly consider the effect of altering the lipid profile on surrogate markers and events associated with atherosclerosis.

Keywords: coronary heart disease, high density lipoprotein cholesterol, low density lipoprotein cholesterol, triglycerides, lipids, total cholesterol, apolipoproteins, lipid lowering drugs


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