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Current Clinical Pharmacology


ISSN (Print): 1574-8847
ISSN (Online): 2212-3938

Peri-Procedural Care of Renal Nerve Ablation Candidates

Author(s): Costas Tsioufis, Kyriakos Dimitriadis, Costas Thomopoulos, Dimitris Tsiachris, Alexandros Kasiakogias, Konstantinos Kintis, Dimitris Flesas, Vasilios Papademetriou and Christodoulos Stefanadis

Volume 8 , Issue 3 , 2013

Page: [217 - 223] Pages: 7

DOI: 10.2174/1574884711308030008

Price: $58


Percutaneous catheter-based transluminal renal nerve ablation (RNA) by delivery of radiofrequency energy constitutes a novel therapeutic strategy for the treatment of resistant hypertension. The sympathetic nervous activation to the kidney and the sensory afferent signals to the central nervous system represent the targets of RNA. In this review we summarize current recommendations for appropriate patient selection for RNA and multimodal strategies in order to optimize pharmacological treatment for resistant hypertension. The safety and efficacy of the RNA based on published trials are also presented. Furthermore, a detailed description of the periprocedural management, the methodology of the RNA procedure and appropriate follow-up are provided. In conclusion, in order to improve the overall clinical outcome and achieve optimal management of resistant hypertensive patients before and after the RNA, experienced and certified centers are of major importance.

Keywords: Invasive procedure, renal denervation, resistant hypertension.

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