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Current Vascular Pharmacology

Eiditor-in-Chief

ISSN (Print): 1570-1611
ISSN (Online): 1875-6212

General Review Article

Renal Dysfunction Following Elective Endovascular Aortic Aneurysm Repair

Author(s): Djodje Radak, Mihailo Neskovic, Petar Otasevic and Esma R. Isenovic*

Volume 17 , Issue 2 , 2019

Page: [133 - 140] Pages: 8

DOI: 10.2174/1570161115666171116163203

Price: $58

Abstract

Abdominal aortic aneurysm (AAA) is a degenerative disease of the aortic wall with potentially fatal complications. Open repair (OR) was considered the gold standard, until the emergence of endovascular aneurysm repair (EVAR), which is less invasive and equally (if not more) effective. As the popularity of endovascular procedures grows, related complications become more evident, with kidney damage being one of them. Although acute kidney injury (AKI) following EVAR is relatively common, its true incidence is still uncertain. Also, there is insufficient data concerning long-term renal outcomes after EVAR, especially with repeated contrast agent exposure. Despite the lack of firm evidence on the effectiveness of individual strategies, it is evident that prevention of AKI following EVAR requires a multifactorial approach. This review focuses on recent findings based on human studies regarding the current evidence of renal impairment after EVAR, its quantification and strategies for its prevention.

Keywords: Endovascular aneurysm repair, acute kidney injury, contrast-induced nephropathy, OR, EVAR, Scr.

Graphical Abstract
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