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Current Pharmaceutical Design

Eiditor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

The Therapeutical Effect of Chinese Medicine for the Treatment of Atherosclerotic Coronary Heart Disease

Author(s): Jian Zhang , Hui Meng, Yi Zhang , Xuefeng Zhang , MingYan Shao, Chun Li * and Pengfei Tu*

Volume 23 , Issue 34 , 2017

Page: [5086 - 5096] Pages: 11

DOI: 10.2174/1381612823666170803101602

Price: $58

Abstract

Coronary heart disease (CHD) is the leading cause of mortality in the world and atherosclerosis is the main cause of CHD. Traditional Chinese medicines have been applied in the treatment of CHD for centuries. In the recent years, clinical trials have been carried out to evaluate the efficacies of Chinese medicine. Meanwhile, extensive studies have also been carried out to explore the underlying pharmacological mechanisms of Chinese medicine. In this review, we will summarize the commonly prescribed Chinese medicine and patent Chinese drugs in treating patients with atherosclerotic CHD and review published clinical trials of Chinese medicine in treating CHD. The anti-atherosclerosis mechanism of Chinese medicine will also be reviewed. Finally, challenges and opportunities facing application of Chinese medicine in the treatment of CHD will be presented.

Keywords: Coronary heart disease, Atherosclerosis, Chinese medicine, clinical trials, pharmacological mechanisms, patent Chinese drugs.


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